Increased public attention to the problems with the IRB system?

Which of the following brought increased public attention to the problems with the IRB system?
A. Death of Research Subject (Jesse Gelsinger)
B. HHS Inspector General Report of 1998
C. 1983 Presidential Commission Report”
D. Shut Downs” by OHRP

Answer:

The death of Jesse Gelsinger brought increased public attention to the problems with the IRB system.

Explanation:

The correct answer is A. Death of Research Subject (Jesse Gelsinger). Jesse Gelsinger was a research subject who died in a gene therapy trial at the University of Pennsylvania in 1999. This high-profile case brought significant attention to the problems with the Institutional Review Board (IRB) system, which is responsible for ensuring the ethical conduct of research involving human subjects.

The other options listed are also related to issues with the IRB system, but the death of Jesse Gelsinger had a particularly strong impact on public awareness and scrutiny of the IRB system.

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